ylaC [2017-05-09 15:36:34]

RNA polymerase sigma factor YlaC

locus: BSU14730

pI: 9.28

mw: 20.78 kDa

protein length: 173 aa

gene length: 519 bp

function: transcription

product: RNA polymerase sigma factor YlaC

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]

Gene

Coordinates: 1,544,085 → 1,544,606

The protein

Protein family

• ECF subfamily (according to Swiss-Prot)

Effectors of protein activity

• YlaD acts as anti-sigma [Pubmed|16728958]

Expression and Regulation

Operons

• genes: [gene|6BB9336E8F5007274026A89BFC3744B52F28E42D|ylaA]-[gene|0703D458DB489F49150DD9E3477A87DC354A7B7F|ylaB]-[gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]-[gene|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD]
  description: [Pubmed|16501307]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16501307], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|544344B61A804F367BB726976E0C87B61998490A|YlaC]: sigma factor, [Pubmed|16501307], in [regulon|544344B61A804F367BB726976E0C87B61998490A|YlaC regulon]

  regulatory mechanism

  • [protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]: activation, [Pubmed|16501307], in [regulon|2C6386E9A63F410558D168798D077DF91590F454|Spx regulon]

  regulation

  • [protein|search|Spx]: transcription activation [Pubmed|16501307]

• genes: [gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]-[gene|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD]
  description: [Pubmed|16501307]

  regulation

  • [protein|search|Spx]: transcription activation [Pubmed|16501307]

Biological materials

Mutant

• MGNA-B356 (ylaC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1355 NBRP B. subtilis, Japan]
• 1A908 ( ''ylaC''::''kan''), [Pubmed|15838020], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A908&Search=1A908 BGSC]

References

Reviews

• 24921931

Original publications

• 16501307,16728958,17675383,20817771